Shi-Yan Yan

Single-Cell eQTL Mendelian Randomization and Colocalization Analysis Reveals Immune Cell-Specific Genetic Insights into Functional Dyspepsia

Background Functional dyspepsia (FD) is a common gastrointestinal disorder characterized by multiple clinical symptoms, complex pathophysiology, and limited therapeutic agents. Emerging evidence indicates a role for immune dysregulation in the pathogenesis of FD; however, immune cell-specific gene regulatory mechanisms...