Effects and potential mechanisms of astragaloside IV in animal models of renal fibrosis: a systematic review and meta-analysis
Background Renal fibrosis is the principal pathological hallmark of progressive chronic kidney disease (CKD). However, the clinical availability of effective, targeted anti-fibrotic therapeutics remains severely constrained. Astragaloside IV (AS-IV), a predominant bioactive metabolite isolated from Astragali Radix, has...