Shi-Zhang Chen

Efficient Preparation of pH-Sensitive Core–Shell Drug-Loaded Hydrogel Microcapsules and Their Application in Ulcerative Colitis Treatment

Conventional microsphere drug carriers for ulcerative colitis (UC) face challenges such as limited residence time, variable drug release, and an increased risk of systemic exposure and side effects. In this study, pH-sensitive, core–shell hydrogel microcapsules were designed and fabricated using a BUCHI B-390 microsphe...