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Author

Shiang Y. Lim

2 papers indexed here

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Open access Aug 2026

The Drp1 inhibitor DRP1i2 confers cardioprotection against doxorubicin-induced cardiotoxicity

Anthracyclines such as doxorubicin are highly effective chemotherapeutic agents, but their clinical use is limited by dose-dependent cardiotoxicity associated with mitochondrial dysfunction. Dysregulated mitochondrial dynamics, particularly excessive dynamin-related protein 1 (Drp1)-mediated fission, has been implica...

Yali Deng, S. Bass-Stringer, S. Bond et al. · 0 citations
Open access Aug 2026

An Integrated Cardiac Microtissue Proteome Map Extends Therapeutic Remodeling by Nanovesicles

It is defined that administration of NVs (from human induced pluripotent stem cell origin) during reoxygenation during reoxygenation significantly increase CM survival and preserve contractility function and the findings provide an advanced human stem cell-based platform to understand underlying mechanisms of IRI and a...

Jonathan Lozano, J. Lees, Jonathon Cross et al. · 0 citations

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