Open access
Aug 2026
Targeting MYCN Degradation by HLB-0532259 Induces Senescence in Retinoblastoma
Targeted MYCN degradation by HLB-0532259 effectively inhibits RB growth and induces a DNA damage–associated senescence program, highlighting targeted MYCN degradation as a promising therapeutic strategy for MYCN-driven RB.
Junjie Tang, Zhihui Zhang, Jianjie Lv et al.
· Investigative Ophthalmology... · 0 citations