Gas6/Axl-mediated macrophage hyporesponsiveness drives severe pulmonary mucormycosis in diabetic mice
Background Pulmonary mucormycosis is a life-threatening fungal infection with a mortality rate exceeding 50%, and diabetes mellitus is one of its strongest risk factors. However, the molecular mechanisms linking diabetes to impaired pulmonary innate immunity remain poorly understood. Methods A streptozotocin-induced ty...