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Shih-Jen Tsai

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Open access Oct 2026

Association of the major depressive disorder-associated locus rs12415800 with bipolar disorder in a Taiwan Biobank–NHIRD linked cohort

Background Genome-wide association studies in East Asian populations have identified the gene variant, rs12415800, of the Sirtuin 1 gene (SIRT1) as a major depressive disorder (MDD) risk locus with the A allele conferring increased risk. Accumulating evidence suggests that SIRT1-related genetic effects extend beyond MD...

Mu-N. Liu, Kan-Chih Chen, Ding-Lieh Liao et al. · 0 citations
Open access Aug 2026

Cross-Modal Brain Network Disruptions in Schizophrenia: Insights from Multiplex Modeling and Transcriptomic Associations.

Multiplex network modeling uncovers cross-modal disruptions in brain organization in SCZ and links these alterations to specific molecular pathways and glial-neuronal substrates, providing multiscale insights into the disorder's neurobiology.

Wei Zhao, Hanrui Chen, Hairong Xiao et al. · 0 citations

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