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Shih-Shuan Fang

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Review Open access Aug 2026

Impact of Menopausal Hormone Therapy on cognitive function and dementia Risk: A systematic review and meta-analysis focusing on the timing hypothesis and administration route

The relationship between menopausal hormone therapy (MHT) and the trajectory of cognitive function in midlife and later life remains one of the most consequential and contested questions in women’s health. The “critical window” or timing hypothesis posits that the cognitive consequences of exogenous estrogen depend on...

Shih-Shuan Fang, Sheng-Han Chen · 0 citations
Review Open access Jul 2026

Artificial intelligence-driven radiomics in neuroimaging for neurodegenerative disease diagnosis and prognosis: a systematic review

AI-driven radiomics demonstrates potential for improving neuroimaging-based diagnosis and prognosis of neurodegenerative diseases, but the field remains substantially limited by methodological heterogeneity, insufficient external validation, high risk of bias, and critical reproducibility challenges including scanner v...

Shih-Shuan Fang, Sheng-Han Chen · 0 citations
Review Open access Jul 2026

Wearable AI for continuous pediatric patient monitoring: a systematic review and meta-analysis

Wearable continuous monitoring devices integrating analytical algorithms show promising diagnostic accuracy and potential clinical benefits in pediatric populations, however, the evidence base remains limited by moderate heterogeneity and a predominance of observational designs.

Shih-Shuan Fang, Sheng-Han Chen · 0 citations
Review Open access Jul 2026

Pediatric autoimmune encephalitis: diagnostic delay and long-term neurocognitive outcomes - a narrative review

The contemporary spectrum of paediatric autoimmune encephalitis is reviewed, including anti-NMDAR encephalitis, MOG antibody-associated disease overlap syndromes, and seronegative AE phenotypes, with emphasis on early recognition, diagnostic algorithms, immunotherapy, and long-term outcomes.

Wan-Ling Lin, Shih-Shuan Fang, Sheng-Han Chen · 0 citations

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