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Shiho Kato

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Open access Sep 2026

Reduced HMGCR Expression in Clear Cell Renal Cell Carcinoma Is Associated With Poor Patient Prognosis

Background/Aim Renal cell carcinoma (RCC) is a heterogeneous malignancy, with clear cell renal cell carcinoma (KIRC) being the most common subtype, characterized by von Hippel–Lindau (VHL) tumor suppressor gene inactivation and hypoxia-inducible factor (HIF) pathway activation, leading to enhanced angiogenesis and tumo...

Etsushi Akitaya, Yuzuki Nakamura, Shiho Kato et al. · 0 citations

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