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Shijun Chen

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Open access Aug 2026

Single-cell transcriptomics identifies a putative perivascular macrophage–endothelial MIF–ACKR3 axis associated with endothelial activation in acute traumatic brain injury

Background Blood–brain barrier (BBB) disruption is a hallmark of acute traumatic brain injury (TBI), yet the immune–vascular mechanisms underlying endothelial dysfunction remain incompletely understood. Perivascular macrophages (PVMs) are strategically positioned to modulate cerebrovascular homeostasis, but their role...

Yan-Ya Lin, Cheng-Yu Lin, Jianhui Chen et al. · 0 citations

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