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Aug 2026

Chemo-enzymatic synthesis of a flexible spacer-modified β-sitosterol derivative with preserved cholesterol-lowering activity.

BACKGROUND Phytosterols, particularly β-sitosterol, exhibit well-recognized cholesterol-lowering activity; however, their practical application is constrained by rigid molecular structures and limited structural tunability. Rational molecular modification combined with the introduction of flexible linkers may provide a...

Ya-Qing Zhang, Shilin Hu, Huijie Cao et al. · 0 citations
Conference Open access 2026

Advances in the Biosynthesis of Natural Products of Plant Origin

This article systematically reviews the latest progress in the biosynthesis of plant natural products, focusing on the synthesis pathways of key compounds such as terpenoids and alkaloids, as well as the strategies for constructing microbial factories and the key challenges of heterologous products.

Shilin Hu · 0 citations

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