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Author

Shiqi Lin

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Aug 2026

EAAT1 sustains redox homeostasis and temozolomide resistance through glutamate-dependent regulation of the Keap1/Nrf2 axis in glioblastoma.

Glioblastoma (GBM) exhibits profound metabolic and redox adaptation that supports tumor progression and therapeutic resistance. Here, we identify the glutamate transporter EAAT1 (SLC1A3) as a critical regulator of glutamate-dependent redox homeostasis in GBM. Analysis of TCGA and CGGA datasets showed that EAAT1 express...

Lu-Fei Chen, Ru-Ying Lin, Yong-Pei Xu et al. · 0 citations
Open access Jul 2026

Shared genetic architecture between schizophrenia and subcortical brain susceptibility phenotypes.

The shared genetic architecture between SCZ and subcortical brain susceptibility phenotypes is dissected by integrating large-scale genome-wide association study data with quantitative susceptibility mapping (QSM) phenotypes across 16 subcortical regions, highlighting pathways that may offer novel therapeutic strategie...

Yingying Xie, Jiaojiao Du, Yao Zhao et al. · 0 citations

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