Design, Discovery, Synthesis, Molecular Docking, MD Simulation, and In Vitro Biological Evaluation of Thiazolidinedione-Clubbed Benzimidazole Hybrids as Potential Anticancer Agents.
INTRODUCTION/OBJECTIVE Breast cancer is a major global health issue. A new series of thiazolidinedione-benzimidazole hybrid derivatives (TBZ1-15) was developed and tested for anticancer properties against the MCF-7 breast cancer cell line using the MTT assay. Among these compounds, TBZ-13 showed the greatest cytotoxici...