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Author

Shota Sasagawa

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2 papers indexed here

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Oct 2026

Molecular landscape of anaplastic transformation in pancreatic ductal adenocarcinoma.

Pancreatic ductal adenocarcinoma (PDAC) with anaplastic features is a rare and highly aggressive subtype with an extremely poor prognosis. However, the molecular mechanisms underlying anaplastic transformation remain poorly understood. To characterize the anaplastic transformation molecular landscape, we analyzed genom...

Akimasa Hayashi, Shota Sasagawa, Takahiro Shibayama et al. · 0 citations
Open access Sep 2026

Single-cell profiling identifies endothelial and tubular transcriptional alterations associated with rapid kidney function decline in low-proteinuric diabetic kidney disease

Some patients with diabetic kidney disease (DKD) experience rapid loss of kidney function despite minimal proteinuria; however, the cellular and pathological features associated with this phenotype remain unclear. In this study, we aimed to characterize the cell-specific transcriptional and pathological alteratio...

Shunichiro Tsukamoto, Ryosuke Jikuya, H. Wakui et al. · 0 citations

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