Advanced quantitative mapping of Alzheimer’s disease neuropathology and microglial activation in post-mortem hippocampal tissue
We developed a high-throughput imaging workflow to spatially map Alzheimer’s disease (AD) pathology in postmortem hippocampal and medial temporal lobe sections from 65 University of Southern California Alzheimer's Disease Research Center (USC ADRC) cases classified by low, intermediate and high levels of AD neuropath...