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Shreya Tripathi

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Open access Sep 2026

DDX39A unwinds viral RNA G-quadruplexes to limit α-Synuclein amyloidogenesis.

Amyloid aggregates of α-Synuclein are hallmarks of Parkinson's disease (PD) and related neurodegenerative disorders. Literature suggests that mRNA G-quadruplexes (rG4s) bind to α-Synuclein, facilitating its amyloidogenesis. In parallel, α-Synuclein interacts with RNA-binding proteins (RBPs) within cytosolic RNA-protein...

Aanchal Jain, Shreya Tripathi, Cheshta Agarwal et al. · 0 citations

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