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Author

Shreyas S. Rao

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Sep 2026

Protein-modified hyaluronic acid hydrogels to elucidate microenvironment-mediated chemotherapy response in triple negative brain metastatic breast cancer.

Brain metastatic breast cancer (BMBC) remains a major clinical challenge, in part, due to the development of drug resistance. However, the mechanisms associated with response to therapy remain poorly understood. In this work, we developed hyaluronic acid (HA)-based hydrogels functionalized with tunable concentrations o...

Paromita Sarker, Kendall Dornan, Shreyas S. Rao · 0 citations
Review Aug 2026

Drug resistance in breast cancer brain metastasis: mechanisms and therapeutic strategies.

This comprehensive review highlights BMBC resistance mechanisms, drawing from preclinical models, clinical studies, and genomic analyses, and highlights the potential for personalized, multi-targeted approaches to improve patient outcomes in BMBC.

Paromita Sarker, Shreyas S. Rao · 0 citations

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