Evaluation of extracellular vesicles released by 3D spheroids and 2D conventional cell culture of the SKOV3 ovarian cancer cell line
Cancer cells communicate with the surrounding tumour microenvironment by secreting extracellular vesicles (EVs), referred to as exosomes, which play a critical role in cancer progression by transferring bioactive cargo including proteins, lipids, mRNAs, miRNAs, and DNA fragments to healthy cells, enabling distant organ...