circRNA−miRNA interactions (CMIs) regulate downstream gene expression through the miRNA sponge mechanism and contribute to the progression of various diseases. Although computational methods have advanced the prediction of potential CMIs, existing approaches still face challenges such as sparse association networks,...
Zhe-Qi Song, Shan-Chen Pang, Yun-Yin Li et al.· ACS Synthetic Biology· 0 citations
The molecular functions of the CDK9/positive transcription elongation factor b (P-TEFb) axis, its role in super-enhancer-driven oncogenic programs, and the mechanisms by which CDK9 inhibition promotes apoptosis, epigenetic derepression, and tumor microenvironment remodeling are summarized.
Ti-Yao Liu, Zhongran Liu, Wen-Jing Wei et al.· Expert opinion on therapeuti...· 0 citations
High-order dynamic disentangled framework for predicting ncRNA-drug resistance associations is proposed, suggesting that HDBI provides an effective and interpretable framework for prioritizing ncRNA-mediated drug resistance associations and guiding downstream mechanistic investigation.
Tiyao Liu, Shu-Dong Wang, Baoming Feng et al.· Journal of Chemical Informat...· 0 citations
MVII-GCL is proposed, a novel multitask prediction framework built upon multiview information integration and graph contrastive learning that supports robustness against data sparsity and noise and its ability to discover potential associations.
Shudong Wang, Bo Yue, Tiyao Liu et al.· ACS Synthetic Biology· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.
