Shu-Guang Zhen

Construction of naringenin-loaded chitosan/sodium alginate nanocomposite gels and their controlled-release kinetics in simulated gastrointestinal media

Naringenin has gastrointestinal pharmacological potential, but poor aqueous solubility, rapid crystallization and limited intestinal residence constrain oral formulation performance. This study evaluated whether coupled tripolyphosphate (TPP) and calcium-ion gelation could produce chitosan/sodium alginate (CS/ALG) nano...