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Shu-Jun Lu

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Sep 2026

Targeting the Snail1-ATGL-Ferroptosis-EMT Axis via AKT-GSK3β Signaling: Low-Dose Colchicine Attenuates Idiopathic Pulmonary Fibrosis.

BACKGROUND The mechanisms underlying colchicine's (COL's) anti-fibrotic effects in idiopathic pulmonary fibrosis (IPF) remain unclear. Ferroptosis-associated redox imbalance and epithelial-mesenchymal transition (EMT) are well-recognized central drivers of IPF progression, yet the upstream regulatory mechanisms linking...

Lei-Lei Shi, Si-Yu Zhan, Xing-Kai Wang et al. · 0 citations

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