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Open access Oct 2026

Time-dependent associations of documented low-dose aspirin administration with 28-day mortality and early safety outcomes in adults with sepsis: a MIMIC-IV cohort study

Associations between aspirin use and sepsis outcomes may reflect treatment timing and clinical selection. This retrospective Medical Information Mart for Intensive Care IV (MIMIC-IV) study included 31,888 adults with Sepsis-3. T0 was defined as the later of intensive care unit (ICU) admission or suspected in...

Chao-Liang Hu, Deng-Wei Cheng, Shu-Li Hu · 0 citations
Open access Sep 2026

Rhapontigenin Alleviates Sepsis‐Associated Acute Kidney Injury and Is Accompanied by Modulation of Ferroptosis, Inflammation, and NF‐κB Signaling

ABSTRACT Sepsis‐associated acute kidney injury (SA‐AKI) is a common complication in critically ill patients and is associated with high mortality. Evidence suggests that ferroptosis‐related lipid peroxidation and inflammatory responses contribute to renal injury. The potential effects of rhapontigenin (Rha), a natural...

Jing Kuang, Xiao-Yun Zhu, Jun Fang et al. · 0 citations

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