Open access
Aug 2026
Integrative multi-omics identifies a four-gene diagnostic signature linking immune dysfunction and airway remodeling in COPD
Four lung-derived COPD-associated candidate genes were identified and CEP55 and ATP6V0D2 showed the strongest peripheral-blood diagnostic performance and biological plausibility, supporting their prioritization as candidate circulating biomarkers for further validation.
Wen-Bo Du, Yu-Kun Wang, Xiang Li et al.
· Therapeutic Advances in Resp... · 0 citations