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Shu-Qun Zhang

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Open access Sep 2026

Multiplatform single-cell and spatial transcriptomics reveal sex-specific malignant states and architecture in male breast cancer

Male breast cancer (MBC) is rare and remains largely managed using knowledge derived from female breast cancer. Here, we generated a multiplatform single-cell and spatial transcriptomic atlas integrating scRNA-seq, SeekSpace, Visium HD, Xenium In Situ, and multiplex immunohistochemistry data from male and female breast...

Hao-Yuan Shi, Xiu-Li Zhang, Shou-Liang Cai et al. · 0 citations
Review Oct 2026

Izalontamab brengitecan for HR+/HER2- breast cancer in China (PANKU-Breast01): a randomised, phase 3 trial.

Iza-bren significantly improved progression-free survival versus chemotherapy, and median progression-free survival assessed by Blinded Independent Central Review was 8·2 months (95% CI 6·9-8·6) versus 4·0 months (2·9-4·3; HR 0·41 [95% CI 0·33-0·53).

B. Lan, Ye-Hui Shi, Xi-Ying Shao et al. · 0 citations
Sep 2026

ZUP1 as a Novel Potential Oncogenic Driver and Prognostic Biomarker in Breast Cancer.

This study identifies ZUP1 as a potential oncogenic factor and a robust independent prognostic biomarker in breast cancer and suggests that ZUP1 is a novel multifaceted biomarker with significant implications for personalized treatment strategies in breast cancer.

Weimiao Li, Changyou Shan, Shu-Qun Zhang et al. · 0 citations

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