Shu-Ting Cheng

Sustained hypoxia induces divergent response patterns in cardiac metabolic-immune adaptation and circadian rhythm regulation

Objective Chronic hypoxia is a critical pathological factor in cardiovascular disease, yet the molecular mechanisms underlying cardiac adaptation to sustained hypoxic stress remain incompletely understood. Methods With 3 GEO datasets, we performed comparative transcriptomic analysis across three hypoxia paradigms (sust...