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Shu-Yan Sheng

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Open access Oct 2026

Myeloid Suppressor Cells Drive HCC Invasiveness via the THBS1-SDC4 Pathway.

This study provides mechanistic insight into how M-MDSCs are activated within the HCC tumor microenvironment and subsequently drive tumor cell EMT through THBS1-SDC4 signaling, and indicates the THBS1-SDC4 axis may represent a therapeutically targetable pathway to restrain M-MDSC-mediated tumor aggressiveness and modul...

Si-Yuan Liu, Jing-Hua Gu, Shu-Yan Sheng et al. · 0 citations

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