Shuai-Bo Wang

Single-cell transcriptomics reveals a complex cell-cell communication network driven by myofibroblast-derived collagen in esophageal squamous cell carcinoma.

Fibroblasts are pivotal regulators of tumor development, progression, and therapeutic resistance in human malignancies. However, their functional diversity and cellular heterogeneity in esophageal squamous cell carcinoma (ESCC) remain largely elusive. In the present study, we constructed a high-resolution single-cell t...