Puji Zhichuang suppositories alleviate acetic acid-induced hemorrhoid-like anorectal inflammation model may involve reduced the PI3K-Akt signaling pathway.
Hemorrhoids are commonly associated with inflammatory manifestations. Puji Zhichuang suppositories (PJZC) have been widely applied in the treatment of hemorrhoids; however, their underlying therapeutic mechanisms remain insufficiently understood. Therefore, this study investigated the mechanisms of PJZC in inflammatory...