Shuai Zhang

Characterizing the tumor microenvironment at the single-cell level reveals the potential immune evasion mechanism in giant cell tumor of bone

Giant cell tumor of bone (GCTB) is intermediate, locally aggressive primary bone tumor that usually occur in long bones and typically present as lytic lesions, leading to cortical expansion or destruction with a soft-tissue component. At present, the main treatment of GCTB is surgical curettage and bone cement fillin...