Virtual Screening, Molecular Dynamics, and Density Functional Theory Identify Piperolein A as a Putative Dual PPARα/γ Modulator Relevant to Radiation‐Induced Cognitive Decline
Radiation‐induced cognitive decline (RICD) is a debilitating late effect of cranial radiotherapy characterized by persistent oxidative stress, neuroinflammation, and impaired hippocampal neurogenesis. Given the established roles of peroxisome proliferator‐activated receptors α and γ (PPARα/γ) in regulating inflammato...