Isatin-based Strategies for Microbial Infections: A Multifaceted Perspective.
Novel chemotherapeutic drugs that can fight multidrug-resistant bacteria are desperately needed due to the fast growth of antimicrobial resistance (AMR). As a favoured scaffold in medicinal chemistry, the naturally produced indole derivative isatin (1H-indole-2,3-dione) is found in microorganisms, plants, and the metab...