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Shubhi Khandelwal

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Sep 2026

Itraconazole and Lacosamide Combination Therapy Rescues CGG Repeat Expansion Induced Neurotoxicity in Fragile X-Associated Tremor/Ataxia Syndrome.

Carriers of the fragile X messenger ribonucleoprotein 1 (FMR1) gene have an elevated risk of developing Fragile X-associated tremor/ataxia syndrome (FXTAS), a progressive late-onset neurodegenerative disorder. Expansion of CGG trinucleotide repeats within the 5' untranslated region leads to RNA-mediated toxicity and pr...

Aditi Pramod Kumari, Smita Karati, Soumalya Das et al. · 0 citations

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