Open access
Aug 2026
Qingzhu granule mitigates acute gouty arthritis through HIF-1α-dependent glycolytic metabolic reprogramming of M1 macrophages
Background Acute gouty arthritis (AGA) is an acute inflammatory disorder triggered by the deposition of monosodium urate crystals (MSU) in the joints, clinically characterized by severe pain and transient limitation of joint mobility. Without proper intervention, recurrent episodes can lead to irreversible joint deform...
Yu-Lin Qi, Wen-Wen Li, Qing Wang et al.
· Frontiers in Immunology · 0 citations