BACKGROUND
Interim analysis of the Neotorch study demonstrated significant benefit in event-free survival (EFS) and major pathological response (MPR) rate for perioperative toripalimab plus chemotherapy in patients with resectable Stage Ⅲ non-small cell lung cancer (NSCLC). Here, we report the final analysis results of...
Zi-Ming Li, L. Wu, W.-X. Wang et al.· Annals of Oncology· 0 citations
PURPOSE
MET amplification accounts for up to 30% of acquired resistance to EGFR-TKI, especially following third-generation EGFR-TKI treatment, yet precision-targeted therapeutic options remain limited. Early-phase studies demonstrated promising antitumor activity with the MET-TKI dalmelitinib combined with the third-ge...
Zi-Ming Li, Xiao-Rong Dong, Yan Yu et al.· Journal of Clinical Oncology· 0 citations
Ociperlimab and tislelizumab±chemotherapy demonstrated a manageable safety profile and preliminary antitumor activity in patients with NSCLC or ES-SCLC and should be interpreted with caution.
Shun Lu, Yan Yu, Jun Zhang et al.· Journal for ImmunoTherapy of...· 0 citations
The role of Olvi-Vec as an oncolytic immunotherapy for cancer treatment warrants additional study, and the clinical effect observed in this patient may be related to Olvi-Vec-mediated changes in the tumor microenvironment, potentially leading to platinum re-sensitization.
Yun Chen, Zhi-Quan Qin, Zi-Ming Li et al.· Frontiers in Oncology· 0 citations
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