Natural compounds targeting glycolysis and TME in ovarian cancer: from metabolic crosstalk to therapeutic potential
Ovarian cancer (OC) cells promote rapid proliferation via aerobic glycolysis and build an immunosuppressive microenvironment at the same time; therefore, this glycolytic pathway is now a potential drug target. Existing glycolysis inhibitors are limited by off-target toxicity, drug resistance, and variable efficacy acro...