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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Shun Wan

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Sep 2026

PRDX1 facilitates USP7-dependent stabilization of SCD1 and promotes bladder cancer progression.

Bladder cancer is characterized by redox adaptation and metabolic plasticity, but the mechanisms linking these processes remain incompletely understood. Integrating bulk, single-cell, and spatial transcriptomic analyses, we identified PRDX1 as a malignant epithelial cell-associated factor linked to adverse outcome. Gen...

Li Wang, Jian-Wei Yang, Shun Wan et al. · 0 citations
Jul 2026

Single-cell and spatial transcriptomics identify CAPG as a key driver of cisplatin resistance in bladder cancer

This study links resistance-associated cellular states to a functionally validated regulator and provides an integrative framework for identifying clinically relevant regulators of chemotherapy resistance in bladder cancer.

Jian-Wei Yang, Xiao-Ran Li, Li Wang et al. · 0 citations

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