Open access
Aug 2026
Surviving Fibroblasts After Treatment With Mitomycin C Exhibit SASP‐Like Phenotype After Glaucoma Filtration Surgery
The clinical outcomes of trabeculectomy, a standard glaucoma filtration surgery (GFS), have dramatically improved with the introduction of mitomycin C (MMC), an antimetabolite widely used to inhibit postoperative scarring. MMC exerts anti‐scarring effects primarily by promoting apoptosis and suppressing fibroblast prol...
Akitoshi Kimura, Tomokazu Fujimoto, Satoshi Iraha et al.
· Aging Cell · 0 citations