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Shuntaro Aoi

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Open access Sep 2026

An ALKBH3 Inhibitor HUHS199 Suppresses Proliferation of Glioblastoma Cells by Targeting 1‐Methyladenosine on GADD45A mRNA

Glioblastoma (GBM) is a highly aggressive, poor‐prognosis brain tumor classified as WHO grade IV, for which effective treatments remain limited. Although AlkB homolog 3 (ALKBH3), a demethylase for 1‐methyladenosine (m1A) and 3‐methylcytidine (m3C) in DNA and RNA, has been implicated in cancer cell proliferation, its fu...

Manami Yamada, H. Hase, Honoka Kitamura et al. · 0 citations

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