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Aug 2026

The ARLA1A-NAC089 module coordinates ER phagy with the unfolded protein response to maintain cellular homeostasis in plants.

The endoplasmic reticulum (ER) is a critical quality-control organelle for protein homeostasis within the cell. The accumulation of misfolded or unfolded proteins triggers ER stress, which can be alleviated through the unfolded protein response (UPR) and ER phagy. These processes work in concert to preserve ER homeosta...

Lianming Yang, Weixin Luo, Tingting Huang et al. · 1 citation
Open access Aug 2026

Dysregulation of the GPX4/ACSL4 axis mediates ferroptosis in neurons of T2DD rats

Introduction Diabetes mellitus complicated with depression (T2DD) is different from a single disease. It leads to more severe damage to nerve cells and cognitive dysfunction, and has a poor prognosis. Existing evidence indicates that ferroptosis—a form of programmed cell death driven by iron accumulation and lipid pero...

Yi Wang, Shuo Wang, Shuai Zhao et al. · 0 citations

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