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Shutong Wang

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Open access Aug 2026

High-Quality Complete Genome Assembly of Bacillus velezensis BV2007 and Genomic Insights Into Its Potential for Biocontrol of Apple Valsa Canker

The previous studies in our laboratory have shown that Bacillus velezensis strain BV2007 exhibits a significant biocontrol effect against apple tree canker. In this study, the complete genomic sequence and annotation information of the strain were obtained by using PacBio Revio platform and Illumina sequencing technologies. Sequence analysis results do not include gaps or plasmids. The final assembled genome of strain BV2007 is 3,916,866 bp in length, with an average GC content of 46.46%. It contains 4,020 predicted protein-coding genes, 87 tRNAs, 27 rRNAs, and 16 sRNAs. A total of 13 secondary metabolite biosynthetic gene clusters were identified in the genome, which may contribute significantly to the biocontrol activity of this strain. This genome sequence has provided a basis for further understanding of the biocontrol mechanism of B. velezensis strains.

Yinuo Liu, Tianhao Fu, Xiaohong Luo et al. · 0 citations
Open access Aug 2026

Genome Sequence Resource of Bacillus velezensis Strain H166, a Potential Biological Control Agent for Apple Replant Disease

Bacillus velezensis strain H166, isolated from the apple rhizosphere, exhibits strong biocontrol efficacy against apple replant disease (ARD), a complex soilborne disease in which Fusarium oxysporum can act as an important fungal pathogen. To elucidate the underlying biocontrol mechanisms, a high-quality genome assembly of strain H166 was generated using PacBio HiFi sequencing. The genome of strain H166 consists of a single circular chromosome of 3,929,791 bp with a GC content of 46.5%, and contains 4,035 protein-coding genes, 86 tRNA genes, 27 rRNA genes, and 16 sRNA genes. Twelve secondary metabolite biosynthetic gene clusters were identified, including those associated with fengycin, surfactin, and bacillaene biosynthesis. These gene clusters are presumed to be closely associated with the biocontrol functions of this strain against Apple Replant Disease. The genome sequence provides important foundational data for further elucidating the molecular mechanisms underlying the biocontrol activity of B. velezensis strain H166.

Tianhao Fu, Yinuo Liu, Yanglin Zhang et al. · 0 citations