Glutathione-responsive gambogic acid-conjugated carboxymethyl chitosan/graphene quantum dot nanoparticles for chemo-photothermal-photodynamic synergistic therapy of drug-resistant breast cancer.
AIMS Breast cancer (BC) remains the most prevalent malignancy in women, with conventional chemotherapy limited by drug resistance. This study develops a glutathione (GSH)-responsive nanoplatform combining chemotherapy with phototherapy against drug-resistant BC. METHODS Gambogic acid (GA) was conjugated to carboxymet...