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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Shweta Modgil

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Open access Sep 2026

Targeting prostaglandin catabolism via topical nanotherapy rescues vision in ischemic optic neuropathy

Ischemic optic neuropathy is a leading cause of acute vision loss and currently lacks effective therapy. Here, we identify 15-hydroxyprostaglandin dehydrogenase (15-PGDH), the key enzyme responsible for prostaglandin degradation, as a metabolic checkpoint in ischemic optic neurodegeneration. Analysis of human ischemic...

Shweta Modgil, Rusiou Hsu, M. Shariati et al. · 0 citations
Open access Aug 2026

RGC-specific reversal of lipid peroxidation drives neuroprotection and vision restoration in optic nerve ischemia by targeting GPX4

Lipid peroxidation is established as mechanism of vision loss in NAION, and targeting GPX4 leads to neuroprotection and visual restoration and identifies GPX4 as a key molecular determinant of retinal ganglion cell resilience.

Ming Yang, Jie Pan, Shweta Modgil et al. · 0 citations

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