Shweta Sunil Nambiar

GNA15 as a regulator of tumor–immune crosstalk: oncogenic signaling, microenvironmental remodeling, and implications for targeted immunotherapy

GNA15 is a Gαq-family G protein whose physiological expression is largely restricted to hematopoietic cells. Nevertheless, aberrant upregulation has been reported in six histologically distinct malignancies, with elevated expression consistently associated with adverse clinical outcomes. Unlike the ubiquitously express...