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Si-Cheng Zhao

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Open access Sep 2026

Chronic Stress Promotes Gastric Cancer Metastasis by Inducing Microbiota‐Associated Kynurenine Accumulation and Macrophage Remodeling

ABSTRACT Chronic stress frequently occurs in patients with cancer, yet how stress is translated into pro‐metastatic programs remains unclear. Here, using chronic restraint stress (CRS) in male mice, we show that stress increases metastatic burden and reduces survival in lung metastasis and peritoneal dissemination mode...

Si-Cheng Zhao, Zhi-Yuan Song, Jing-Cheng Zhang et al. · 0 citations

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