Author

Si-Hang Shen

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Review Open access Aug 2026

Immune niches in brain tumors: glial–immune cell interactions and spatial microdomains

The immune microenvironment of brain tumors is characterized by remarkable diversity, where immune cells are not randomly distributed but are systematically organized into specific spatial microdomains. This spatial order is primarily orchestrated by glial cells, including astrocytes, microglia, and oligodendrocyte-lin...

Qian Guo, Si-Hang Shen, Zhou-Yuan Zhang et al. · Acta Neuropathologica Commun... · 1 citation

Sep 2026

Oxidized sodium alginate/carboxymethyl chitosan/γ-polyglutamic acid injectable hydrogels enabling pH-responsive synergistic delivery of antimicrobial agents and metal-polyphenol nanoparticles for diabetic foot ulcer healing.

Chronic diabetic wounds have become a major global health challenge due to the vicious cycle driven by infection, oxidative stress, and inflammation. To address this issue, researchers developed a pH-responsive injectable hydrogel (SCP@QCNPs&DOX). The hydrogel is composed of oxidized sodium alginate, dihydrazide-modifi...

Gui-Xi Wang, Si-Hang Shen, Li-Dong Wang et al. · International Journal of Bio... · 0 citations