Si-Jie Liu

Microglia-neuron communication in ischemic stroke: from homeostatic signaling to pathological remodeling and therapeutic targeting

Ischemic stroke profoundly disrupts the homeostatic dialogue between microglia and neurons, converting a physiological surveillance network into a dynamic, injury-responsive, and spatially heterogeneous communication system. Under physiological conditions, neurons regulate microglia through diverse signaling pathways,...