Si-Jie Ma

Rationally Designed Peptides and Peptoids as Inhibitors of Amyloid-β (Aβ) Aggregation

Peptide and peptoid are two types of peptidomimetics can be used as drugs for diseases. One of the main hallmarks in Alzheimer’s Disease (AD) is Aβ aggregation. Due to the natural affinity between peptide and Aβ proteins, peptide therapeutics are found out to be suitable for the disease, as they are almost nontoxic,...