Paeoniflorin improved intestinal barrier function and immune homeostasis of broiler chickens challenged with Eimeria by modulating gut microbiota and suppressing M1 macrophage-associated inflammatory responses
Coccidiosis caused by Eimeria parasites impairs intestinal function and disrupts immune homeostasis in broilers, leading to substantial economic losses in poultry production. Paeoniflorin (PFN), a monoterpene glycoside with known anti-inflammatory and immunomodulatory properties, has not been extensively studied agains...