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Author

Siwen Dong

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Open access Jul 2026

Induction of paraptotic cell death in breast cancer cells by an iron chelator involved activation of UPR/MAPK pathway and inactivation of PI3K/AKT/mTOR.

The results demonstrated that paraptotic cell death induced by an iron chelator in breast cancer cells was partially involved in Ca2+-mediated ROS production, UPR(unfolded protein response)/MAPKs activation, and PI3K/AKT/mTOR inactivation.

Lei Yuan, Si-Wen Dong, Yong Shao et al. · 0 citations

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