Regulation of PD-L1 expression and secretion by branched-chain amino acids in melanoma and prostate cancer cells
Cancer immunotherapy, particularly immune checkpoint blockade targeting programmed death ligand 1 (PD-L1), has revolutionized cancer treatment. Branched-chain amino acids (BCAAs) are essential amino acids whose metabolism can be an indicator of certain cancers. However, the relationship between branched-chain amino aci...